This study evaluates the technical efficiency of wheat-producing farms in the Samarkand region and identifies the key factors influencing it. The analysis is based on survey data collected from 300 farmers in 2024. A two-stage methodological approach was applied: in the first stage, technical efficiency scores for each farm were estimated using the Cobb-Douglas production function; in the second stage, socio-economic and institutional determinants of efficiency were assessed using the Tobit regression model. The results reveal that the average technical efficiency level is 0.868, indicating that farmers have the potential to increase productivity by 13% using existing resources. According to the Tobit model, household size, the practice of tree planting, and the freedom to use fertilizers have a statistically significant and positive impact on efficiency, whereas membership in agricultural clusters has a significant but negative effect. The findings suggest that enhancing technical efficiency requires liberalizing input use, promoting environmentally friendly practices, and improving institutional frameworks.