This research explores the state regulation of foreign direct investment in Uzbekistan, emphasizing its regional characteristics and the interplay between national and local policies. It examines how the concentration of FDI in regions like Tashkent, Navoi, and Fergana Valley contrasts with the underinvestment in areas such as Karakalpakstan and Surkhandarya. Recommendations for enhancing policy alignment and improving investment conditions are provided to promote balanced economic development across the country.