This study presents an analysis of state policy and mechanisms for creating sustainable financing systems for innovative projects in the Republic of Uzbekistan. It examines existing problems in the development of venture funds, startup ecosystems, and innovation infrastructure, as well as issues related to attracting state grants and foreign investments. The study also explores the necessity of financing through modern technology transfer and venture funds to accelerate innovative activities in the economy. Additionally, it analyzes the state of applied and fundamental scientific research and their effectiveness in being implemented in production.